Mast Cell Activation Syndrome (MCAS)

What is Mast Cell Activation Syndrome (MCAS)?

Mast Cell Activation Syndrome (MCAS) is a chronic condition where mast cells, a type of immune cell, inappropriately release excessive chemical mediators. These mediators can cause an array of symptoms affecting multiple organs and systems, often resembling allergic reactions but without the typical triggers of allergies. Because mast cells exist throughout the body, MCAS symptoms are diverse and can vary greatly from person to person and over time.

If you’re looking for an MCAS Naturopath in Adelaide, Merridy Casson provides a functional medicine approach to help identify triggers and manage symptoms effectively.

Skin Treatment Adelaide

Common Symptoms of MCAS

  • Constitutional symptoms: Fatigue, malaise, sudden hot or cold sensations, inappropriate sweating, and flushing.
  • Skin-related: Rashes, itching, migratory redness, swelling, dermatographism (redness after scratching), poor healing, and nail changes.
  • Respiratory: Cough, shortness of breath, mild wheezing, bronchitis-like symptoms, and obstructive sleep apnoea.
  • Cardiovascular: Palpitations, light-headedness, fluctuating blood pressure (hypertension or hypotension), non-anginal chest discomfort, and vascular malformations.
  • Gastrointestinal: Abdominal pain, bloating post-meals, reflux, nausea, diarrhea or constipation (often alternating), and occasional blood in stool.
  • Urinary: Frequent urination, difficulty initiating urination, painful urination, and sometimes flank pain.
  • Genital tract (especially women): Vulvar or vaginal inflammation, dysfunctional uterine bleeding, painful intercourse, and fertility issues.
  • Neurological: Memory problems, headaches, brain fog, balance issues, mood swings, anxiety, depression, and sleeping disturbances.
  • Anaphylaxis risk: MCAS can cause potentially life-threatening allergic reactions involving rapid heartbeat, low blood pressure, swelling of lips or throat, difficulty breathing, hives, and loss of consciousness.

Prevalence in Australia

It is believed that MCAS is underdiagnosed worldwide, potentially affecting a notable minority of the population possibly tens of thousands. Better awareness and diagnostic criteria are helping identify more cases locally.

Take the Allergy Reactivity MCAS Questionnaire

Complete the Allergy Reactivity MCAS Questionnaire to help understand your symptoms.

Naturopathic Treatment Approaches

A naturopathic approach to MCAS typically involves diet, nutritional supplementation, and lifestyle modifications aimed at reducing mast cell activation and improving overall immune regulation:

1. Diet:

An anti-inflammatory, low-histamine, and low-mast cell triggering diet is recommended, avoiding processed foods, fermented products, alcohol, aged cheeses, and certain fruits and vegetables known to release histamine.

Individual food trigger testing and elimination protocols can help identify personal sensitivities.

2. Nutritional Support:

Supplements such as vitamin C and quercetin (an antioxidant and natural mast cell stabiliser) may reduce mast cell mediator release.

Particular anti-allergy herbs such as albizia, long pepper, ginger, black pepper and several others, can help reduce and control symptoms.

Omega-3 fatty acids can provide anti-inflammatory effects.

Probiotics that support gut barrier function may be beneficial, given the link between gut health and mast cell activity.

Magnesium and B-complex vitamins can support nervous system function and reduce symptoms.

3. Lifestyle Modifications:

Sress management techniques like mindfulness, meditation, and gentle exercise such as yoga can help reduce symptom flares.

Avoidance of known triggers like extremes of temperature, strong fragrances, and environmental toxins is crucial.

Ensuring adequate sleep and hydration supports overall health.

A treatment plan is typically tailored individually to help manage symptoms and reduce anaphylactic risk.

Get in touch to see how Merridy can help

Whether you’re curious about how naturopathy can support your health or you want to discuss your symptoms, Merridy is happy to chat and guide you in the right direction. You’re welcome to call for a quick, no-pressure conversation to see if naturopathic treatment for MCAS is right for you.